
Choosing between gastric sleeve and gastric bypass surgery is a personal and often complex decision. Both are highly effective bariatric procedures, but the right option depends on your medical history, weight loss goals, and lifestyle factors.
Let’s break down the key differences and what you should consider when discussing options with your bariatric team.
Understanding the Procedures
Gastric Sleeve Surgery, also known as sleeve gastrectomy, involves removing about 80% of the stomach. What remains is a narrow, tube-like sleeve. This smaller stomach helps you feel full faster and reduces the production of the hunger hormone ghrelin and increases several hormones that improve glucose control and activate the metabolism such as glucagon-like peptide 1 (GLP-1) and gastric inhibitory peptide (GIP).
Gastric Bypass Surgery, or Roux-en-Y gastric bypass, involves creating a small pouch at the top of the stomach and rerouting a portion of the small intestine. These limits both the amount of food you can eat and how some micronutrients (but not calories) your body absorbs. The hormonal effects are ultimately similar to those seen after a sleeve gastrectomy
Pros and Cons of Each Procedure
Gastric Sleeve is less complex, has a shorter operating time, and doesn’t alter the intestines. It’s a great option for patients who might be taking medications such as Non-steroidal anti-inflammatories (NSAIDs), steroids, medications for autoimmune diseases as there is no compromise of the surgery once it heals. However, it might cause severe reflux in a minority of patients that is significant enough to perform another surgery to address the reflux.
Gastric Bypass, has a slight better control of diabetes but long term weight loss appears to be the same. It is the single best surgery for reflux and might be an even stronger benefit than the weight loss itself. However, it comes with a higher risk of micronutrient deficiencies (iron, calcium, vitamin B12), and complications like connection ulceration, dumping syndrome or internal hernias may occur. Always ask your surgeon if you are able to take a new medication after your bypass.
Long-Term Outcomes and Health Benefits
Both procedures offer significant improvements in obesity-related conditions such as:
- Type 2 diabetes
- High blood pressure
- Sleep apnea
- Joint pain
- High Cholesterol levels
Eligibility and BMI Requirements
You may qualify for bariatric surgery if you meet one of the following:
- A BMI of 35 or higher
- A BMI of 30 or higher with obesity-related health issues like diabetes, sleep apnea, hypertension or high cholesterol
Your surgical team will evaluate other factors too, including your mental health, readiness to change, and any prior surgical history.
Risks and Considerations
Every surgery comes with risks. Understanding these upfront is essential:
- Gastric sleeve can lead to increased acid reflux, nausea, or staple line leaks (though rare). It’s also not reversible.
- Gastric bypass carries a higher risk of dumping syndrome (rapid food emptying into the small intestine), nutrient deficiencies, and bowel obstructions. It’s more technically complex and more difficult to reverse.
Your doctor will help you weigh these risks against the potential benefits based on your medical history.
Frequently Asked Questions
Will I lose more weight with bypass?
Gastric bypass tends to be faster, however at 2 years weight loss is comparable to a sleeve.
Is one surgery safer than the other?
Both are safe when performed by experienced bariatric surgeons. The gastric sleeve has a slightly lower complication rate due to the lack of connections. Long term, the sleeve tends to have less complications than the bypass
Which is better for acid reflux?
Gastric bypass is typically the best option for people with GERD, as it often improves or resolves symptoms. The sleeve tends to improve or not affect reflux in most patients, however a minority of patients may experience worsening reflux, with some requiring surgery to treat it.
Can either surgery be reversed?
Gastric sleeve is considered permanent. Gastric bypass can technically be reversed, but it’s complex and rarely done.
What about pregnancy after surgery?
It’s often recommended to wait at least 18-24 months after surgery before becoming pregnant, giving your body time to stabilize. Many women experience improved fertility after weight loss.
About the Author

Dr. Medrano
Weight loss surgery, Obesity medicine, General surgery
Dr. Medrano, inspired by his surgeon uncles, graduated from Tec de Monterrey in 2014 and trained at Baylor College of Medicine and Houston Methodist Hospital. In 2016, he became the only foreign graduate among 200+ applicants to secure a U.S. surgery residency. After completing a bariatric fellowship at Abington-Jefferson Health, he specialized in robotic-assisted procedures. Now in San Antonio, he’s a leading expert in minimally invasive and robotic surgery.